![]() ![]() These are the melasma treatment options that doctors and RealSelf members say work best.ġ–12 days of downtime (depending on intensity) Results from even the best treatments won't hold if patients don’t apply (and reapply) sunscreen with an SPF of 30+ every day. Improving melasma requires ongoing professional and topical treatments, in combination with diligent sunscreen use and sun avoidance. Even patches that seem to fade completely almost always come back. There is no cure for melasma, so the condition never fully resolves. Unfortunately, all the most effective melasma treatments carry risks of triggering more hyperpigmentation or hypopigmentation (spots that lose pigment and appear lighter than the rest of the skin), so it’s important to ease in, with an abundance of caution, to prevent potential remedies from backfiring and worsening your condition. If you have olive or brown skin, it’s essential to find a dermatologist who’s experienced in treating dark skin tones. Removing old layers of the skin makes room for fresh, healthy cells and brings trapped pigment to the surface so it can be shed. Treatments to improve the appearance of melasma focus on releasing the excess pigment from the skin and encouraging cell turnover. Other factors, like heat, visible light, thyroid disease, and stress, can contribute to or exacerbate melasma. Nissan Pilest, a dermatologic surgeon in Irvine, California. “Sun exposure will immediately ramp up the pigment production, if you aren't protected with a full-spectrum sunscreen,” says Dr. Sun exposure. Sun can both bring on melasma and worsen existing patches, since UV light speeds up melanin production. ![]() ![]() However, most melasma treatments are not safe for women who are pregnant or breastfeeding. Birth control pills and hormone replacement therapies can trigger it as well. Often dubbed “the mask of pregnancy,” the skin condition is especially common in pregnant women, whose estrogen and progesterone levels overstimulate melanin production. According to the American Academy of Dermatology, 90% of people who get melasma are women. We conclude that TA emulsion is an effective cosmeceutical product having a whitening effect on melasma and freckles through inhibition of melanin synthesis, and preventing the appearance of new pigmented spots and freckles.Unlike postinflammatory hyperpigmentation, which is caused by injury or irritation (like acne, eczema, or bug bites), melasma is typically triggered by two main risk factors: hormonal changes and UV radiation from sunlight. As regards the time course, marked improvement was observed within 8 weeks for melasma, but within 12 weeks for freckles therefore, improvement was considered to require at least two months of topical application. No side effect was recognized, so TA emulsion is considered to be safe. At the last observation point, TA emulsion had improved the pigmentation in melasma and freckles in 20 subjects(80%) with melasma and 6 subjects(75%) with freckles. The subjects, 25 with melasma and 8 with freckles, used the TA emulsion for five to eighteen weeks, and the outcome was evaluated based on a doctor’s visual assessment of skin pigmentation. We investigated whether topical application of tranexamic acid(TA) emulsion is effective for improving the pigmentation in melasma and freckles. ![]()
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